Considering what happened to them last year for a similar cover called “Charia Hebdo” this is pretty courageous of them and I fully support them. We are slowly getting bullied into accepting that we don’t have the right to free speech or at least to bear its consequences by some extremists. Why should they make special allowance for one group simply because that group is particularly violent and irrational? To self-censure would be terrible and a failure of all that we in the West hold dear. Freedom of thought and freedom of expression are the foundation of our society.
Note: Charlie Hebdo is not particularly anti-muslim, they are famous for making fun of pretty much everyone in France. Also, the cartoon on the front page is a reference to the French movie Intouchables which is about a rich paraplegic hiring a street-gangsta type of caretaker for a trial run. This is a play on the same context with a rabbi and Mohammed, the prophet. The text inside the bubble roughly means you shall not mock.