The Lethality of Loneliness
For the first time in history, we understand how isolation can ravage the body and brain. Now, what should we do about it?
Sometime in the late ’50s, Frieda Fromm-Reichmann sat down to write an essay about a subject that had been mostly overlooked by other psychoanalysts up to that point. Even Freud had only touched on it in passing. She was not sure, she wrote, “what inner forces” made her struggle with the problem of loneliness, though she had a notion. It might have been the young female catatonic patient who began to communicate only when Fromm-Reichmann asked her how lonely she was. “She raised her hand with her thumb lifted, the other four fingers bent toward her palm,” Fromm-Reichmann wrote. The thumb stood alone, “isolated from the four hidden fingers.” Fromm-Reichmann responded gently, “That lonely?” And at that, the woman’s “facial expression loosened up as though in great relief and gratitude, and her fingers opened.”
Fromm-Reichmann would later become world-famous as the dumpy little therapist mistaken for a housekeeper by a new patient, a severely disturbed schizophrenic girl named Joanne Greenberg. Fromm-Reichmann cured Greenberg, who had been deemed incurable. Greenberg left the hospital, went to college, became a writer, and immortalized her beloved analyst as “Dr. Fried” in the best-selling autobiographicalnovel I Never Promised You a Rose Garden (later also a movie and a pop song). Among analysts, Fromm-Reichmann, who had come to the United States from Germany to escape Hitler, was known for insisting that no patient was too sick to be healed through trust and intimacy. She figured that loneliness lay at the heart of nearly all mental illness and that the lonely person was just about the most terrifying spectacle in the world. She once chastised her fellow therapists for withdrawing from emotionally unreachable patients rather than risk being contaminated by them. The uncanny specter of loneliness “touches on our own possibility of loneliness,” she said. “We evade it and feel guilty.”
Her 1959 essay, “On Loneliness,” is considered a founding document in a fast-growing area of scientific research you might call loneliness studies. Over the past half-century, academic psychologists have largely abandoned psychoanalysis and made themselves over as biologists. And as they delve deeper into the workings of cells and nerves, they are confirming that loneliness is as monstrous as Fromm-Reichmann said it was. It has now been linked with a wide array of bodily ailments as well as the old mental ones.
In a way, these discoveries are as consequential as the germ theory of disease. Just as we once knew that infectious diseases killed, but didn’t know that germs spread them, we’ve known intuitively that loneliness hastens death, but haven’t been able to explain how. Psychobiologists can now show that loneliness sends misleading hormonal signals, rejiggers the molecules on genes that govern behavior, and wrenches a slew of other systems out of whack. They have proved that long-lasting loneliness not only makes you sick; it can kill you. Emotional isolation is ranked as high a risk factor for mortality as smoking. A partial list of the physical diseases thought to be caused or exacerbated by loneliness would include Alzheimer’s, obesity, diabetes, high blood pressure, heart disease, neurodegenerative diseases, and even cancer—tumors can metastasize faster in lonely people.
The psychological definition of loneliness hasn’t changed much since Fromm-Reichmann laid it out. “Real loneliness,” as she called it, is not what the philosopher Søren Kierkegaard characterized as the “shut-upness” and solitariness of the civilized. Nor is “real loneliness” the happy solitude of the productive artist or the passing irritation of being cooped up with the flu while all your friends go off on some adventure. It’s not being dissatisfied with your companion of the moment—your friend or lover or even spouse— unless you chronically find yourself in that situation, in which case you may in fact be a lonely person. Fromm-Reichmann even distinguished “real loneliness” from mourning, since the well-adjusted eventually get over that, and from depression, which may be a symptom of loneliness but is rarely the cause. Loneliness, she said—and this will surprise no one—is the want of intimacy.
Today’s psychologists accept Fromm-Reichmann’s inventory of all the things that loneliness isn’t and add a wrinkle she would surely have approved of. They insist that loneliness must be seen as an interior, subjective experience, not an external, objective condition. Loneliness “is not synonymous with being alone, nor does being with others guarantee protection from feelings of loneliness,” writes John Cacioppo, the leading psychologist on the subject. Cacioppo privileges the emotion over the social fact because—remarkably—he’s sure that it’s the feeling that wreaks havoc on the body and brain. Not everyone agrees with him, of course. Another school of thought insists that loneliness is a failure of social networks. The lonely get sicker than the non-lonely, because they don’t have people to take care of them; they don’t have social support.
To the degree that loneliness has been treated as a matter of public concern in the past, it has generally been seen as a social problem—the product of an excessively conformist culture or of a breakdown in social norms. Nowadays, though, loneliness is a public health crisis. The standard U.S. questionnaire, the UCLA Loneliness Scale, asks 20 questions that run variations on the theme of closeness—“How often do you feel close to people?” and so on. As many as 30 percent of Americans don’t feel close to people at a given time.Loneliness varies with age and poses a particular threat to the very old, quickening the rate at which their faculties decline and cutting their lives shorter. But even among the not-so-old, loneliness is pervasive. In a survey published by the AARP in 2010, slightly more than one out of three adults 45 and over reported being chronically lonely (meaning they’ve been lonely for a long time). A decade earlier, only one out of five said that. With baby-boomers reaching retirement age at a rate of 10,000 a day, the number of lonely Americans will surely spike.
Obviously, the sicker lonely people get, the more care they’ll need. This is true, and alarming, although as we learn more about loneliness, we’ll also be better able to treat it. But to me, what’s most momentous about the new biology of loneliness is that it offers concrete proof, obtained through the best empirical means, that the poets and bluesmen and movie directors who for centuries have deplored the ravages of lonesomeness on both body and soul were right all along. As W. H. Auden put it, “We must love one another or die.”
